Nevus Comedonicus: An Updated Review
Identifieur interne : 003356 ( Main/Exploration ); précédent : 003355; suivant : 003357Nevus Comedonicus: An Updated Review
Auteurs : Georgi Tchernev [Bulgarie] ; Julian Ananiev [Bulgarie] ; Kristina Semkova [Bulgarie] ; Lyubomir A. Dourmishev [Bulgarie] ; Jaqueline Schönlebe [Allemagne] ; Uwe Wollina [Allemagne]Source :
- Dermatology and Therapy [ 2193-8210 ] ; 2013.
Abstract
The intention of this review on nevus comedonicus (NC) is to update on clinical features, pathogenesis, and therapy. NC is a rare epidermal nevus type. It is part of the nevus comedonicus syndrome, a neurocutaneous disorder with ocular, skeletal, and central nervous symptoms. Recently, acne-related signaling pathways and somatic mutations of tyrosine kinase receptors have been identified and may play a role in NC pathogenesis. On preexistent NC secondary skin tumors can develop, which are often benign. Treatment options of NC include topical therapy, laser, and surgery.
Url:
DOI: 10.1007/s13555-013-0027-9
PubMed: 23888253
PubMed Central: 3680637
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en"><p>The intention of this review on nevus comedonicus (NC) is to update on clinical features, pathogenesis, and therapy. NC is a rare epidermal nevus type. It is part of the nevus comedonicus syndrome, a neurocutaneous disorder with ocular, skeletal, and central nervous symptoms. Recently, acne-related signaling pathways and somatic mutations of tyrosine kinase receptors have been identified and may play a role in NC pathogenesis. On preexistent NC secondary skin tumors can develop, which are often benign. Treatment options of NC include topical therapy, laser, and surgery.</p>
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<author><name sortKey="Beverdam, Eg" uniqKey="Beverdam E">EG Beverdam</name>
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<author><name sortKey="Krekels, Ga" uniqKey="Krekels G">GA Krekels</name>
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<name sortKey="Ananiev, Julian" sort="Ananiev, Julian" uniqKey="Ananiev J" first="Julian" last="Ananiev">Julian Ananiev</name>
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